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Try, Try Again: Stories of ADHD Medication Trials and Errors

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With dozens of different ADHD medications on the market, it’s likely one will work well for you — but it may not be the first, or second, medicine you try.

On average, children try 2.75 different medications and adults try 2.56 prescriptions before finding one that works for them, according to a recent ADDitude survey of more than 11,000 readers.Adults and caregivers reported that the process of searching for the right medication — the one with highest efficacy, fewest side effects, and covered by insurance — is often frustrating, but essential.

Persevering through the often confusing, time-consuming, and inconvenient process leads to better management of ADHD symptoms in the end for most.

Read more on additudemag.com
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Atypical Brain Connectivity Linked to ADHD: NIH Study
March 27, 2024ADHD symptoms in children are associated with unusual interactions between the frontal cortex and deep centers of the brain where information is processed, according to a recent report in the American Journal of Psychiatry.1 These findings may help inform additional research into the ADHD brain that leads to more effective treatments and interventions.A research team from the National Institute of Mental Health (NIMH) and National Human Genome Research found children with ADHD demonstrated heightened connectivity between brain structures involved in learning, movement, and reward, and frontal areas of the brain that regulate emotion, attention, and behavior.“The present findings suggest that these brain alterations are specifically associated with ADHD and are not indicative of general features of childhood psychopathology or influenced by comorbid symptoms,” the study’s authors wrote.Researchers have long suspected that ADHD symptoms result from atypical interactions between the frontal cortex and these deep information-processing brain structures. However, the study’s authors noted that prior studies testing this model returned mixed results, possibly due to the small size of the studies they suggested.The present study examined more than 10,000 functional brain images of 1,696 youth with ADHD and 6,737 without ADHD aged 6 to 18.
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