Japanese researchers have discovered a deficiency in the brains of people with schizophrenia. The findings could lead to the development of new drug therapies.
For the study, researchers at the RIKEN Center for Brain Science (CBS) in Japan conducted post-mortem exams (autopsies) and discovered that schizophrenia was linked to lower-than-normal levels of S1P, a type of fatty molecule found in the white matter of the brain.
In recent years, drug therapy for schizophrenia has come to a halt. Most schizophrenia drugs currently available are based on dopamine, but they are ineffective in about one out of every three patients.
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