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‘Super-Agers’ Show Resistance to Proteins Tied to Alzheimer’s

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therapies that may allow more of us age better and retain more of our cognitive abilities as we get older.”While some insights have been collected on amyloid pathology in super-agers, there is no in vivo evidence on tau pathology due to what had been a dearth of available imaging techniques.Data from the Alzheimer’s Disease Neuroimaging Initiative was used to create three age- and education-matched groups of 25 super-agers, 25 normal-agers and 25 patients with mild cognitive impairment, all above 80 years old.In addition, 18 younger, cognitively normal, amyloid-negative controls were included in the comparison as a reference group.

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