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Whole-Genome Study Finds Previously Undetected Schizophrenia Mutations

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A new study, published in Nature Communications, suggests that ultra-rare structural genetic variants could play a role in schizophrenia.

Most genetic research on schizophrenia has sought to understand the role genes play in the development and heritability of schizophrenia.

And while many discoveries have been made, there are still many missing pieces. Now, scientists at the University of North Carolina (UNC) School of Medicine have conducted the largest-ever whole genome sequencing study of schizophrenia to provide a more complete picture of the role the human genome plays in this disease. “Our results suggest that ultra-rare structural variants that affect the boundaries of a specific genome structure increase risk for schizophrenia,”

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