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What to Know About Potential COVID-19 Vaccine Side Effects

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By JoNel Aleccia, Kaiser Health News and Liz Szabo, Kaiser Health News Drugmaker Pfizer is expected to seek federal permission to release its COVID-19 vaccine by the end of November, a move that holds promise for quelling the pandemic, but also sets up a tight time frame for making sure consumers understand what it will mean to actually get the shots.

This vaccine, and likely most others, will require two doses to work, injections that must be given weeks apart, company protocols show.

Scientists anticipate the shots will cause enervating flu-like side effects — including sore arms, muscle aches and fever — that could last days and temporarily sideline some people from work or school.

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