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What Is Mast Cell Activation Syndrome?


Medically reviewed by Dr. Kate Rowland, MD, MS, FAAFP Your immune system is complex — a combination of cells, chemicals and organs work together to ward off invaders that could wreak havoc on your system.

Of course, if you’re familiar with a chronic illness like an autoimmune disorder, you also know how this can go awry: Suddenly a system designed to protect you is now the cause of your symptoms.

The same can happen when your mast cells, an important type of defender cell found in your immune system, aren’t functioning as they should.

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