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Science Explains Why Asthma Severity Increases at Night

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The Proceedings of the National Academy of Sciences. ADVERTISEMENTAsthma, a chronic lung disease, causes airways to become inflamed, swollen, and narrow.

Symptoms include difficulty breathing, chest pain, cough, wheezing, and mucus buildup. While it affects people throughout the day, doctors noticed nocturnal asthma for centuries.

ADVERTISEMENTFor instance, in 1698, the physician Sir John Floyer experienced this phenomenon firsthand. He noticed increasing asthma severity at about 1 or 2 AM compared to daytime symptoms.

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