Free Radical Biology and Medicine on January 6, 2022. ADVERTISEMENT “We’ve found that cannabinol protects neurons from oxidative stress and cell death, two of the major contributors to Alzheimer’s,” says senior author Pamela Maher, a research professor and head of Salk’s Cellular Neurobiology Laboratory. “This discovery could one day lead to the development of new therapeutics for treating this disease and other neurodegenerative disorders, like Parkinson’s disease.” ADVERTISEMENT Cannabinol comes from the cannabis plant and resembles THC molecularly.
However, it differs since it’s not psychoactive and isn’t as heavily regulated by the FDA. Prior research by Maher’s lab discovered that CBN protects the brain, but they weren’t sure how until this study.
Now, they’ve uncovered the mechanism driving CBN to protect brain cells from oxidative damage and death.In the study, Maher’s colleagues examined the process of oxytosis or ferroptosis.
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