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Q: “What Are the Long-Term Effects of ADHD Medication on the Brain?”

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Q: “What do we know about the long-term effects of ADHD medication on the brain? My child has ADHD and benefits from taking medication, but I worry about what medication will do to the brain, if anything, after taking it for years.

On that note, does my child have to be on ADHD medication for life?”ADHD medications, especially stimulants, dramatically reduce the core symptoms of attention deficit hyperactivity disorder, which include inattention, distractibility, hyperactivity and disorganization.

We know this from decades of research, including the hundreds of studies published every year on the efficacy of ADHD medications.First, it is important to know that there are three areas of the brain that are smaller in children with ADHD than they are in children without ADHD1 — the prefrontal cortex, the fronto-striatal-cerebellar projections, and the caudate nucleus.

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