My article for the Telegraph:Back in the early 1950s scientists were baffled by one aspect of life itself. Our cells were full of proteins whose properties depended on their precise shapes, and the key feature of life was the ability to copy itself, but how on earth do you copy three-dimensional shapes?
The unexpected answer was that you don’t: you copy a one-dimensional, linear sequence in a recipe book called DNA, which automatically determines how each protein folds into its shape.Surprisingly, until last week, working out how this folding worked was beyond even big computers: tiny shifts in angles could result in wildly different shapes, and forecasting what shape would result from what sequence was as hard as predicting the weather..
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